Monday, October 26, 2026 · Edition updated 6:00 AM ETMON, OCT 26 editionNext edition in Next in --:--:--
Intelligence Verdict
AI startups

Science, materials and math

AI for physics, chemistry, new materials and mathematics, often with robotic labs. Each company's last reported valuation, next to what it has actually shipped.

  • 10young companies
  • 5valued at $1 billion or more at their last closed round
  • 2with no public product yet, by our search
10 companies

Who they are, what they've built.

Read Oct 20, 2026. Valuations and amounts are copied as each source states them; open "Founders, funding and notes" on a card for every round and its source.

CuspAI

United Kingdom · founded 2024

“a startup developing AI models for chemistry that counts several AI luminaries among its scientific advisors” Fortune

$2.6Bvaluation, Series B, Jul 20, 2026

LatestRaised a $450M Series B at a reported $2.6B valuation and launched the AI Materials Foundry with more than 45 partner organizations.Jul 20, 2026 · Quartz (via Yahoo Finance), Cris Tolomia; valuation attributed to Bloomberg

Founders, funding and notes
Founders
  • Chad Edwards: co-founder and CEO; "a chemist turned technology entrepreneur" who previously worked at Quantinuum (SiliconANGLE, Sep 10, 2025)
  • Max Welling: co-founder; AI expert and former vice president of technology at Qualcomm (SiliconANGLE, Sep 10, 2025)
Funding, as reported
  • Sep 10, 2025, Series A: $100 million, valued at $520 million (one unnamed source; CuspAI declined to comment). Investors named: NEA (co-lead), Temasek (co-lead), NVentures, Samsung Ventures, Hyundai Motor Group (Fortune, Sep 10, 2025)
  • Jul 20, 2026, Series B: $450 million, valued at $2.6 billion (per Bloomberg, as cited by Quartz). Investors named: Kleiner Perkins (co-lead), NEA (co-lead), Bezos Expeditions, Glade Brook Capital Partners, Lux Capital, AMD Ventures, UK Sovereign AI Venture Fund, Temasek, Prosus (Quartz (via Yahoo Finance), Cris Tolomia; valuation attributed to Bloomberg, Jul 20, 2026)
Note

Series B figures are from Quartz, which attributes the valuation to Bloomberg; Quartz is not on the trusted-outlet list and the Bloomberg piece was not fetched. Advisers include Yann LeCun and Geoffrey Hinton, per the same report.

Valuation, Jul 20, 2026 · Description, Sep 10, 2025

Axiom Math

United States

“Mathematics-focused artificial intelligence startup” SiliconANGLE

$1.6Bvaluation, Series A, Mar 12, 2026

LatestRaised $200M Series A at a $1.6B valuation led by Menlo Ventures.Mar 12, 2026 · Axios Pro, Pro Rata Premium: First Look (Lucinda Shen)

Founders, funding, outside checks and notes
Founders
  • Carina Hong: Stanford Ph.D. student; MIT bachelor's in mathematics and physics; Oxford master's; 2023 Morgan Prize winner (SiliconANGLE, Oct 2, 2025)
  • Shubho Sengupta: former Meta Platforms AI researcher who helped develop Meta's Llama LLMs (SiliconANGLE, Oct 2, 2025)
Funding, as reported
  • Oct 2, 2025, Seed (reported as a first funding round): $64 million, valued at $300 million. Investors named: B Capital (lead), Greycroft, Madrona Ventures, Menlo Ventures (SiliconANGLE, Oct 2, 2025)
  • Mar 12, 2026, Series A: $200 million, valued at $1.6 billion. Investors named: Menlo Ventures (lead), Greycroft, Madrona, B Capital (Axios Pro, Pro Rata Premium: First Look (Lucinda Shen), Mar 12, 2026)
Outside checks
Note

Founding year not stated on any page fetched. Forbes Italia says Hong left Stanford after a conversation 'last autumn' (article dated 2025-10-02). Series A source is an Axios Pro newsletter item; Pulse 2.0 (2026-03-13) reports 'above $1.6 billion'. The company blog lists posts through Oct 2026.

Valuation, Mar 12, 2026 · Description, Oct 2, 2025

Harmonic

United States · founded 2023

“a startup focused on AI systems designed to solve mathematical problems” Axios

$1.45Bvaluation, Series C, Jan 15, 2026

LatestNvidia joined Harmonic's $120M Series C at a $1.45B valuation.Jan 15, 2026 · Axios

Founders, funding and notes
Founders
  • Vlad Tenev: co-founder; Robinhood CEO (TechCrunch, Jul 28, 2025)
  • Tudor Achim: CEO and co-founder (TechCrunch, Jul 28, 2025)
Funding, as reported
  • Jul 28, 2025, Series B: $100 million, valued at $875 million. Investors named: Kleiner Perkins (lead) (TechCrunch, Jul 28, 2025)
  • Nov 25, 2025, Series C: $120 million, valued at $1.45 billion. Investors named: Ribbit Capital (lead), Sequoia Capital, Index Ventures, Kleiner Perkins, Emerson Collective (new) (Harmonic (company), Nov 25, 2025)
  • Jan 15, 2026, Series C (Nvidia joins): part of the $120 million Series C, valued at $1.45 billion. Investors named: Nvidia (new) (Axios, Jan 15, 2026)
Note

Harmonic says Aristotle produced formally verified (Lean 4) solutions to five of six 2025 IMO problems, which it calls gold medal-level; this is the company's claim and no third-party evaluation was found. Reuters puts total raised at $295 million. The newest item on Harmonic's news page is dated 2026-02-11 (a $300,000 donation to Lean FRO).

Valuation, Jan 15, 2026 · Description, Jan 15, 2026

Periodic Labs

United States

“Periodic Labs is an AI research and deployment company creating models and autonomous labs to accelerate science.” Periodic Labs, company-reported

$1.3Bvaluation, Seed, Sep 30, 2025

Reported $7.5B in a report not confirmed by the company, May 7, 2026

LatestAnnounced Periodic Neon and said it "outperforms both Claude Fable 5.1 and GPT-6 Astra for diffraction analysis" (company claim; no third-party benchmark in the post).Sep 15, 2026 · Periodic Labs (company)

Founders, funding and notes
Founders
Funding, as reported
Note

The May 2026 round (at least $500M at $7.5B, led by AMP) comes from people familiar speaking to Forbes; Periodic did not respond and AMP declined to comment. Forbes also cites a March 2026 Bloomberg report of talks at at least $7B. The company launched publicly on 2025-09-30; no founding year is stated on a page fetched.

Valuation, Sep 30, 2025 · Description, Sep 30, 2025

Lila Sciences

United States · founded 2023

“Lila aims to build "scientific superintelligence" by pairing specialized AI models with automated laboratories.” Reuters

$1.3B+valuation, Series A extension, Oct 14, 2025

Reported $8.5B in talks, Jun 3, 2026

LatestBloomberg reported Lila was in talks to raise about $2 billion at about $8.5 billion pre-money, anchored by CalPERS and NVentures; Lila and CalPERS declined to comment.Jun 3, 2026 · Bloomberg News (via Bloomberg Law), Michelle F. Davis

Founders, funding and notes
Founders
Funding, as reported
  • Oct 14, 2025, Series A extension (Series A total $350 million): $115 million, valued at more than $1.3 billion. Investors named: NVentures (Nvidia, new), Flagship Pioneering, General Catalyst, subsidiary of the Abu Dhabi Investment Authority (Reuters (via Yahoo Finance), Krystal Hu, Oct 14, 2025)
  • Jun 3, 2026, Series B (in talks; not confirmed closed): about $2 billion, valued at about $8.5 billion pre-money. Investors named: CalPERS (anchor, per sources), NVentures (anchor, per sources) (Bloomberg News (via Bloomberg Law), Michelle F. Davis, Jun 3, 2026)
Note

Lila was incubated by Flagship Pioneering. Reuters put total funding at $550 million as of Oct 2025. The $2B Series B is from people familiar (Bloomberg); no closing was confirmed on any page fetched. Company calls itself "the world's first Operating System for Science" (company claim).

Valuation, Oct 14, 2025 · Description, Oct 14, 2025

Edison Scientific

United States · founded 2025

“to accelerate discovery across fields by giving every researcher access to an AI scientist” Edison Scientific, company-reported

No valuation reported

LatestIntroduced BixBench-Hypothesis benchmark and an open training dataset (company post).Mar 16, 2026 · Edison Scientific (company)

Founders, funding and notes
Founders
Funding, as reported
  • Dec 18, 2025, Seed: $70 million. Investors named: Triatomic Capital (co-lead), Spark Capital (co-lead), unnamed U.S. institutional biotech investor (co-lead), Pillar VC, Susa Ventures, Striker Venture Partners, Hawktail, Olive Tree Capital (SiliconANGLE, Dec 18, 2025)
Note

Commercial spinout of the non-profit FutureHouse (started 2023). The company reports 79.4% of Kosmos conclusions were accurate, from its own evaluation; no third-party evaluation was found. A $250M valuation for the seed round appears only on Caproasia (not a listed trusted outlet) and is left out.

Description, Mar 16, 2026

“a startup using AI to design advanced materials” Fortune

No valuation reported

LatestRaised a $50M Series B led by Plural; rebranded from Orbital Materials; says a PFAS-free data-center coolant is slated to ship with next-generation GPUs in 2027.May 28, 2026 · Fortune

Founders, funding, outside checks and notes
Founders
  • Jonathan Godwin: cofounder and CEO; former Google DeepMind researcher, five years on AI for science and advanced materials (Fortune, May 28, 2026)
  • James Gin-Pollock: cofounder and CTO; repeat AI founder who sold a company to Shutterstock (Fortune, May 28, 2026)
  • Daniel Miodovnik: cofounder and COO (Fortune, May 28, 2026)
Funding, as reported
  • May 28, 2026, Series B: $50 million. Investors named: Plural (lead), NVentures, Radical Ventures, Compound, Fly Ventures (Fortune, May 28, 2026)
Outside checks
  • UniFFBench, by researchers at IIT Delhi, Intel Labs and NVIDIA, benchmarked six force-field models including Orb against experimental data; Orb "exhibits failure across all elastic tensor components, with MAPE values consistently exceeding 80%" while doing well on structural metrics (preprint). (arXiv 2508.05762 (IIT Delhi, Intel Labs, NVIDIA authors), Aug 2025)
Note

Fortune says the company has offices in London and San Francisco and names no single HQ; country set to UK on the London base. It has a multi-year AWS partnership announced Dec 2024 (per Fortune). Customers are unnamed.

Description, May 28, 2026

Deep Principle (深度原理)

China · founded 2024

“一家成立仅两年的创业公司,用AI来发现新材料,被资本看到了。” 21st Century Business Herald

No valuation reported

LatestReported cumulative funding of nearly RMB 1 billion after a Series A closed in July 2026; named L'Oréal as a seed customer.Sep 19, 2026 · 21st Century Business Herald (21jingji)

Founders, funding, outside checks and notes
Founders
Funding, as reported
Outside checks
Note

The 'what' quote translates as: a startup founded only two years ago that uses AI to discover new materials has caught the attention of capital. Round-by-round amounts before July 2026 come from the company's own news list. No valuation found. Customer results (e.g. L'Oréal: about 80% of recommended molecules outperformed previous ones) are as reported by 21jingji from the company.

Description, Sep 19, 2026

Radical AI

United States · founded 2024

“New York City–based Radical AI is building a self-driving materials lab” R&D World

No valuation reported

LatestR&D World profile of its self-driving materials lab; says the company has not yet moved into manufacturing.Jan 29, 2026 · R&D World, Julia Rock-Torcivia

Founders, funding and notes
Founders
Funding, as reported
  • Jul 20, 2025, Seed (R&D World calls it Seed+): $55 million. Investors named: RTX Ventures (lead, per R&D World), Nvidia, noa, Eni Next, Infinite, AlleyCorp (FinSMEs, Jul 20, 2025)
Note

Smaller than most in this list; included as a distinctive autonomous-lab company. R&D World mentions a later $60M Series A without a date or source; not verified. Gerbrand Ceder (formerly Berkeley Lab's autonomous lab) is Chief Science Officer.

Description, Jan 29, 2026

Entalpic

France · founded 2024

“designs molecules and materials for surface-driven industrial processes” Entalpic, company-reported

No valuation reported
Nothing public found

LatestCompany timeline lists commercial expansion in early 2026 and an experimental lab in Grenoble planned for late 2026. · Entalpic homepage (company)

Founders, funding and notes
Founders
Funding, as reported
Note

Small European company included for EU coverage. Searched the company homepage, Axios Pro and investor pages; the site names an 'Atomistic Discovery Engine' but no dated product, model or paper. Co-lead list comes from investor Cathay Capital's own post. No 2025-2026 funding found.

Description